London, ON.– Scientists at The University of Western Ontario and the Lawson Health Research Institute jointly received more than **$13-million** in support of an array of medical research this week. The Canadian Institutes of Health Research (CIHR) announced operating funding for a total of 28 London projects ranging from research into osteoarthritis and kidney damage to prenatal health and obesity.London researchers continue to do very well in a highly competitive national funding environment.The funding success rate for applications submitted from London scientists to CIHR was 27% while the national average was 17%. **Additional funding results not previously reported** **John MacDonald** received $1,048,740 (5 years) for his project “NMDA Receptors, Metaplasticity and Schizophrenia”. **Ravi Menon** received $912,635 (5 years) for his project “Ultra high field MRI measurements of tissue magnetic susceptibility in Multiple Sclerosis”. **Stefan Everling** received $854,155 (5 years) for the project “Role of frontal cortical projection to the superior colliculus in saccade suppression and task switching in primates”. **Stephen Ferguson** received $758,070 (5 years) for the project “Regulation of Vascular G Protein-coupled Receptor Signal Transduction”. **Giles Santyr** received $367,905 (3 years) for his project “Functional and Metabolic Magnetic Resonance Imaging of Lung Inflammation”. **Gregory Zaric** received $173,829 (3 years) for his project “Economic evaluation of tests to reveal the source of cancers of unknown primary”. **Nica Borradaile** received $91,439 (1 year) for “Roles of elongation factor 1A-1 in apolipoprotein B metabolism and the pathogenesis of nonalcoholic fatty liver disease”. **Lakshman Gunaratnam r**eceived $100,000 (I year) for “Exploiting KIM-1 signalling to ameliorate acute kidney injury through clearance of apoptotic cells”. **Funding results reported today by Lawson Health Research Institute** **Frank Beier** received $713,501 (5 years) for the project, “TGFalpha/EGFR signaling in osteoarthritis”. **Peter Chidiac** received $539,515 (5 years) for the project, “Role of RGS2 in the response of cells to stress”. **Lina Dagnino** received $703,280 (5 years) for the project, “Integrin-linked kinase in epidermal stem cells”. **Neil Duggal** received $325,808 (4 years) for the project, “Metabolic and functional correlates in spinal cord compression measured by Magnetic Resonance Imaging”. **Amit Garg** received funding for four projects: $99,210 (2 years) for “Acute kidney injury from antiviral drugs for herpes infections:A population-based study of older adults”.(Lawson co-applicant - Peter Blake) $139,828 (2 years) for “Electrolyte Disorders from Common Medications:Risk and Mitigation”. (Lawson co-applicant – Jeffrey Reiss) $119,920 (2 years) for “Preoperative Medications and Acute Kidney Injury:A VISION sub-study”. $59,951 (1 year) for “Filtering Medline for Renal Information:Renal Sub-Filters”. **Daniel Hardy** received $364,704 (3 years) for the project, “Molecular mechanisms underlying the in utero origins of hypercholesterolemia”. **Robert Hegele** received $599,814 (5 years) for the project, “Genetic architecture of cardiometabolic risk in families and communities”. **David Heinrichs** received $702,770 (5 years) for the project, “Role of iron and heme binding proteins in pathogenesis of Staphlococcus aureus”. **David Holdsworth** received $752,848 (5 years) for the project, “Single-plane dynamic radiography for quantification of bone and joint motion”. **Anthony Jevnikar** received $609,640 (5 years) for the project, “Regulation of renal tubular epithelial cell injury to promote kidney allograft survival”. **Mellissa Mann** received $833,106 (5 years) for the project, “Molecular analysis of genomic imprint maintenance during embryogenesis”. **Joseph Mymryk** received $807,400 (5 years) for the project, “Molecular genetic analysis of adenovirus E1A function”. **Samuel Siu** received $405,600 (3 years) for the project, “Pregnancy and Subsequent Cardiovascular Risk in Women with Heart Disease”. **Rommel Tirona** received $584,056 (4 years) for the project, “Role of Skeletal Muscle Drug Transporters in Statin-Induced Myopathy.” **Hao Wang** received $316,529 (3 years) for the project, “Mechanisms of Soluable CD83 in Prevention of Antibody Mediated Rejection”. **Kaiping Yang** received $566,323 (4 years) for the project, “Early-life origins of visceral adiposity.” **Ruud Veldhuizen** received $100,000 (1 year) for “The effects of mechanical ventilation on the biophysical properties of pulmonary surfactant”. **Media Contacts:** Maureen Spencer Golovchenko Senior Media Relations Officer The University of Western Ontario 519-661-2111 ext. 85165 Julia Capaldi Communications Consultant Lawson Health Research Institute (519) 646-6100 ext. 61098